Who doesnt want amazing skin? But what makes this miracle ingredient so amazing? Pycnogenol (150 mg/day) reduced LDL and increased HDL cholesterol in a trial of 25 healthy people after 6 weeks [55]. He later extracted proanthocyanidins from the European coastal pine tree, which he named Pycnogenol.. Pycnogenol is not approved by the FDA for medical use. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. The first studied group included 66 healthy subjects in whom the number of muscle cramps was recorded two weeks before entering the study and during the fourth and fifth week. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. Optimal doses of pycnogenol have not been set for any condition. Researchers suggest this benefit may be due to an increase in glutathione and SOD, two antioxidants that may reduce inflammation and oxidative stress in Crohns [76]. Organika Pycnogenol 50mg 50 Tablets . Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. Known for its antioxidant properties, Pycnogenol offers a wide range of potential health benefits. Next, the doctors discuss the link between salt and hypertension, and Dr. Steve gives his insight on drinking red wine for a healthy heart. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. After taking a break for one to two weeks, they can start taking it again for several weeks. Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. The . A small 2012 study on postmenopausal women found that pine bark extract improved hydration and elasticity of skin. It is found primarily in southwestern France and is used to help people with asthma, allergies, hay fever, and other health conditions.. Pycnogenol significantly improved the heavy feeling as well as the swelling. There's good evidence that pycnogenol helps with eye damage caused by diabetes. Pycnogenol completely normalized function. Andrographis is a medicinal herb used to treat many health conditions, such as the common cold, osteoarthritis, and ulcerative colitis. The top benefits of nattokinase include the following: Regulate blood pressure. Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Pycnogenol was featured on The Dr. Oz Show in January 2013, . Depending on the extraction process and the source Pinus species used (P. radiata or P. pinaster), the exact composition will vary. The effect of polyphenolic extract from pine bark, Pycnogenol on the level of glutathione in children suffering from attention deficit hyperactivity disorder (ADHD) [Abstract]. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. For allergies: 50 milligrams twice daily. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. Remember to speak with a doctor before taking Pycnogenol. Benefits Of Pycnogenol To Live Longer - Life Extension The remaining compounds are phenolic acids, which may also have antioxidant activity [1, 2]. The authors attributed the negative results to the short duration of treatment and the low dosages of drug or Pycnogenol. Neuroprotective effect of Pycnogenol® following traumatic brain injury. Pycnogenol is similar to grape seed extract and cocoa polyphenols as those are the three most common . The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for . The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people. There were 88 in the control group and 81 in the Pycnogenol group. A study of 32 people with heart failure lasting 12 weeks suggests that a combination of Pycnogenol with CoQ10 (PycnoQ10) may improve blood pressure, heart function, edema, and capacity for physical activity [40]. Pycnogenol Benefits, Dosage & Side Effects - Ayur Times are clickable links to medically peer-reviewed studies. 1. Some risks associated with Pycnogenol include:, Pycnogenol and other maritime tree barks have not been studied as extensively as traditional medicine. It also appeared to improve their attention span, visual motor skills, and concentration. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. Regulations set manufacturing standards for supplements, but that does not guarantee that they are safe or effective. Four hundred years later, a French researcher named Jacques Masquelier did some studies to understand why this natural remedy was so effective. With time, the participants were able to handle more UV radiation without experiencing skin damage [63]. However, some of these other pine bark extracts can have different active compounds, which may affect their biological activity. Plus, it reduced total and LDL (bad) cholesterol. Its been noted that taking OPCs and vitamin C supplements at the same time could increase blood pressure if you have hypertension. Studies on human subjects have reported few side effects - even . In this study, 155 peri-menopausal women were enrolled in a double-blind, placebo-controlled study. $47.99. Your email address will not be published. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. Prenatal nutrition can be confusing. from the bark of the French maritime pine tree. However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. If youre native to Oregon, you likely know all about marionberries. Regardless, a natural option is available and far worth the wait. Pycnogenol: A miracle component in reducing ageing and skin disorders. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. Score one for diabetes control and fewer risk factors for the heart. Eye health. The study suggests it may increase desire, arousal, lubrication, orgasm, satisfaction and reduce pain [70]. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. She loves communicating science and empowering people to achieve their optimal health. Luteolin: Potential Benefits + Foods & Side Effects The active ingredients in pycnogenol can also be extracted from other sources, including peanut skin, grape seed, and witch hazel bark. As noted, aspirin can cause severe gastrointestinal issues. (2012). Rare cases of liver disease. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. Protection from inflammation, immunosuppression and carcinogenesis (2017). But what are its health benefits? In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). Jonathan Ritter, PharmD, PhD (Pharmacology), Small molecule antioxidants (phenolic acids, catechin, and taxifolin) are quickly absorbed and begin to act in the body within 30 min, The remaining more complex antioxidants (long chains of procyanidins) reach the gut, where your, The microbiome-produced active compounds appear in blood 6 h later and remain for at least 14 h, Pycnogenol is standardized to contain 70 5% procyanidins, which should be on the label, Pycnogenol standardization doesnt determine other major active compounds, which can vary. are clickable links to these studies. People who use the supplement along with their traditional medication usually take smaller doses than those who only take the supplement. , Allergy: "Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. L-arginine is more effective when paired with L-citrulline or pycnogenol to combat erectile dysfunction and improve exercise performance. ( 1) 2. (11, 12), While both eliminate pain, the pine bark extract is a far better choice. Regardless of what youre using it for, its best to start with the lowest possible dose. PQQ (pyrroloquinoline quinone), also called methoxatin, is a vitamin-like compound that exists naturally in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk . Thus, this powerful extract works as a natural ear infection remedy while improving balance and preventing hearing loss. Top Anti-Aging Properties Of Pycnogenol - Life Extension Studies were conducted in Turkey on subjects who underwent abdominal surgery to determine if the pine bark extract could help reduce the inflammation. Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. Pycnogenol-treated patients had significant improvement in symptoms as well as a reduction in leg swelling as compared to those not receiving treatment. Joe Cohen flipped the script on conventional and alternative medicine and it worked. There havent been any studies looking at long-term liver damage. DOI: Dvorkov M, et al. 12 Benefits of Pycnogenol (Pine Bark Extract) According to Studies (adsbygoogle = window.adsbygoogle || []).push({}); Heart Palpitations at Night: Common Causes and How to Treat, Essential Oils for Cough, Cold and Congestion, Sudden High Blood Pressure: Causes, Symptoms and Prevention Tips, Sore Throat on One Side: 7 Causes and Treatments, Natural Remedies for the Burning Sensation in Your Stomach After Eating, Hibiscus Tea: Health Benefits, Nutrition, Side Effects, and Recipes, Vegetable Oil Substitutes: 5 Healthy Alternatives for Baking, Frying, and More, How to Treat Nausea After Eating Eggs or Chicken, Diarrhea after Eating: Causes and Natural Treatments, Top 11 Homeopathic Remedies for High Blood Pressure, Heavy Breathing: Common Causes and Treatments, Pineapple Juice for Cough: Effective Homemade Cough Remedies, Pain in the Left Temple of the Head: 10 Causes and Treatments. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. Two doses of 100 mg of Pycnogenol were taken two to three hours before flights and two additional capsules taken six hours later then one capsule the next day. This supplement possibly activates the immune system. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. Pycnogenol may stimulate the immune system. It may cause side effects such as: Dizziness. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. Note that each number in parentheses [1, 2, 3, etc.] Used early on, it may prevent eye damage and blindness from diabetes [34]. $109.99. We avoid using tertiary references. For mild high blood pressure: 200 milligrams daily. In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. Lower Your Blood Pressure Naturally with Nattokinase The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Blood pressure is an important measure of how much blood is pumping from your heart to the rest of your body. More specifically, because it strengthens the capillaries in the retina, Mirtogenol can help prevent retinopathy. So it may not be safe for people with immune disorders, such as: It's not known if pycnogenol is safe for children or for women who are pregnant or breastfeeding. Pycnogenol (100 mg/day) may reduce leg swelling, spider veins, and cramps according to a study of 133 women with varicose veins who recently gave birth. Results showed that one month of Pycnogenol led to a significant reduction of hyperactivity with improvement in attention and visual-motor coordination and concentration, as compared to no positive effects in the placebo group. (4). All rights reserved. It also lessened the amount of asthma medication they needed. This bark extract has been around for about 450 years. Pycnogenol has several benefits to your health and beauty. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. DOI: Trebatick J, et al. Pine bark distill has been studied regarding its relationship to exercise performance, oxidative stress and excitement to torso that has been imposed by exercise. During week, five without, treatment, reduction of cramps was maintained in all three groups. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. In the Pycnogenol-treated group, blood sugar levels were significantly lowered as compared to those not on Pycnogenol. First and foremost, start eating an anti-inflammatory Local Raw Honey (Bee Pollen) Considering how good it tastes, having some raw honey Apple Cider Vinegar (ACV) You can now find high-quality apple cider vinegar in . editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. Memorial Sloan-Kettering Cancer Center web site: "About Herbs: Pine Bark Extract. What Are These Tiny Red Spots on My Skin (Petechiae)? is a clickable link to peer-reviewed scientific studies. In the study, many of the participants on Pycnogenol reduced their dosage of high-blood-pressure medication (nifedipine) [37]. According to research, Pycnogenol may have a multitude of health benefits, which are likely due to this extracts antioxidant and anti-inflammatory properties. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. Pine Bark Extract Health Benefits, Nutrition and How to Use - Dr. Axe Lower the risk of Alzheimer's disease. Potential benefits of folic acid include a reduced risk of cancer, improved cognitive function, stronger bones, enhanced heart health, better pregnancy outcomes and reduced symptoms of restless legs syndrome. New research has shown promising results for those dealing with erectile dysfunction (ED) and diabetes. Moreover, Pycnogenol group either reduced or discontinued the use of asthma drugs. In 22 German heavy smokers, platelet aggregation was prevented by 500 mg of aspirin or 100 mg Pycnogenol. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. It also slightly decreased blood pressure and increased testosterone [67]. But two months ago, erectile dysfunction health food with the help of the Divine Tool Alliance, the price of all materials related to the puppet mechanism was raised by 20 erectile dysfunction health food 30 , and the price of selling the puppet was reduced by 10. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. Disease of the retina in the eye. All rights reserved. Additionally, the results showed that the extract has significant anti-pseudomonas activity, making it a potential natural remedy and possible preventive measure for infections. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. Why Pycnogenol May Be the Only Supplement You'll Ever Need This study adds to a body of research showing the benefits of Pycnogenol for improving circulation and blood flow, strengthening the vascular system and managing cholesterol. Our team aims to be not only thorough with its research, but also objective and unbiased. Boost gastrointestinal health. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. . 2005 - 2023 WebMD LLC. The goal of this study was to evaluate if Pycnogenol could prevent deep venous thrombosis (DVT) and superficial vein thrombosis (SVT) in eight-hour flights in 196 subjects at risk of these conditions. High levels of both of these are considered risk factors for heart disease. Talk to your own doctor about Pycnogenol if youre interested in using it for your own health. The supplement significantly reduced hot flashes, night sweats, mood swings, irregular periods, loss of libido, and vaginal dryness. Add to Cart. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Pycnogenol health benefits. In contrast, bleeding still occurred in the control group [61]. Speak with your doctor before supplementing. Flavonoids and proanthocyanidins within these fruits can . For diseases of the retina, including those related to diabetes: 50 milligrams three times daily. Circulation and Jet Lag on Long Flights. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. Can you get pycnogenol naturally from foods? In theory, pine bark may lower blood pressure and blood sugar level, and these effects have also been reported in some RCTs. In 1535, a French explorer by the name of Jacques Cartier found himself ice-bound on the St. Lawrence River. Placebo capsules were given to control subjects at the same times. Millions are hospitalized each year for . Unlike drug manufacturers, the makers of supplements dont have to show their products are safe or effective before selling them on the market. Typical doses range from 50 milligrams to 450 milligrams per day. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. However, it is also important to see beyond the pyncogenol marketing campaign and understand the possible dangers associated with this natural supplement. Theres evidence that Pycnogenol may be a promising nootropic for various groups of people, including middle-aged professionals, students, and people with mild cognitive decline like brain fog. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. 6 Amazing Benefits of Nattokinase | Organic Facts Theres some evidence that Pycnogenol acts similar to a sustained-release formulation. You can refer to the National Institutes of Healths dosage guidelines for specific conditions. Note that the numbers in parentheses (1, 2, etc.) It also may enhance swimming, biking, and running scores in professional athletes preparing for a triathlon (at 150 mg/day). The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. The most effective blood sugar-lowering dose was 200 mg/day higher doses had no further benefit [33]. Another 2006 study examined the effects of the antioxidant activity of pine bark extract on oxidative stress, which is thought to be one of the nongenetic factors contributing to ADHD. A study of 58 people with high blood pressure suggests that even lower doses (100 mg/day) may improve blood vessel health and reduce markers of high blood pressure (endothelin-1) after 12 weeks. Another one of its exemplary effects is helping manage blood pressure levels. A clinical trial of 57 ADHD children found that daily Pycnogenol (1 mg/kg) for one month may reduce hyperactivity symptoms. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). Pycnogenol is thought to be an antioxidant that helps protect cells from damage. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. 14 Health Benefits of Pine Bark Extract - Blog - iHerb.com Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. Dizziness. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. For example, Enzogenol is an extract from a pine that grows in California and Mexico (Pinus radiata) that may have cognitive-enhancing effects. Pycnogenol-treated patients reported significant improvement with knee pain, as compared to the placebo group. You may want to start slow, taking smaller amounts, to ensure that your body works well with the OPCs found in pine bark extract. Lowers Blood Pressure. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Headaches. They could interact with medicines to suppress the immune system, chemotherapy drugs, and blood thinners. Chestnut seed extract did not do as well. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. Pycnogenol acts as a sustained-release formulation. Pain score in the Pycnogenol-treated group was reduced by 56%, as compared to 9.6% reduction in the placebo group. They were treated with 200 mg of Pycnogenol daily or with placebo. According to a Japanese study, the combination of Pycnogenolt and L-arginine may produce the results youre looking for, making the bedroom a much happier place. The study participants symptoms started to return a month after they stopped taking pine bark extract.